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Clinical aspects of rotavirus disease in children from South-East of Romania

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ABSTRACT
Background. Gastroenteritis with rotavirus is the leading cause of severe diarrhea among infants and young children. The aim of the study was to evaluate the clinical aspects of the rotavirus gastroenteritis comparatively with non-rotavirus disease.
Material and methods. We conducted an observational, retrospective study, that included children hospitalized in the Clinical Hospital of Infectious Diseases from Constanța, Romania, between 2011-2012. We analyzed the medical records of the patients and extracted demographic data, temperature, frequency of vomiting and diarrheic stools, degree of dehydration, duration of parenteral rehydration and hospitalization. We compared two groups of children: 505 with rotavirus disease and 100 with non-rotavirus disease.
Results. There were statistically significant differences (p=0.001) between the mean age of the two groups, the number of days of hospitalization, the maximum number of stools per day, the maximum number of vomiting per day. There were no statistically significant differences between the two groups regarding the maximum temperature value (p=0.96).

Conclusions. Evolution of the rotavirus disease is more severe and prolonged comparatively with nonrotavirus gastroenteritis.
Key words: rotavirus, gastroenteritis, children.

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Simona Diaconu, Simona Claudia Cambrea, Lucian Cristian Petcu and Sorin Rugina

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