Elevations of cardiac troponin T (cTnT) can predict death and clinical events in patients without overt heart disease, according to a large cohort study. The results of this study were published in the October issue of the Journal of the American College of Cardiology, authored by Martin J. Holzmann et al. 20,000 patients presenting with chest pain but without acute myocardial infarction or other known cardiac disease, have been evaluated. In these patients, elevated but stable levels of hs-cTnT predicted risk over about 3 years. A small, but persistent, elevation of hs-cTnT was more closely associated with the risk of future heart failure hospitalization than with future myocardial infarction. This elevation may be due to previously unidentified, subclinical heart disease.