Introduction. Exaggerated placental site reaction is a rare benign non-neoplastic lesion and presents with infiltration of the endometrium and myometrium by intermediate trophoblastic cells at the implantation site. This reaction may occur following healthy or ectopic pregnancy, aborts, or molar pregnancy. The diagnosis is only histopathological.
Case report. We present a 44-year-old woman with prolonged menstrual bleeding, high levels of beta-hCG and ultrasound finding mimicking submucosal fibroid. Hysterectomy was performed because of the formation in the uterine cavity. The diagnosis made was exaggerated placental site reaction.
Conclusions. Exaggerated placental site reaction is a benign condition, but this lesion has to be differentiated from placental site nodule, placental site trophoblastic tumor and choriocarcinoma because the latter require aggressive treatment.
Keywords: exaggerated placental site reaction, intermediate trophoblast, submucosal fibroid.
Angel D. YORDANOV
Clinic of Gynecologic Oncology, University Hospital “Dr. Georgi Stranski”, Pleven, Bulgaria
Address: Georgi Kochev 8A, Pleven, Bulgaria
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