The paper aims to highlight the changes of lysosomes evidenced by electron microscopy in biopsy specimens taken from two cases of psoriasis vulgaris. Through detailed analysis of microscopic images, from smooth sections x320, up tox610,000 images, next to the aspects specific histo-pathological psoriasis vulgaris stands apart the abundance of lysosomes in various stages of development.
Corroborating lysosomal changes with augmentation of the disease and posttherapeutic free radicals, noted in a previous paper, one can advance the hypothesis that the pathogenesis of psoriasis vulgaris includes lysosomes developments in close connection with the release of free radicals.
Abbreviations: Micrometre (μm), Minutes (min), Tetrahydrofuran (THF), Nanometer (nm)
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