ISSN ONLINE: 2558-815X
ISSN PRINT: 1584-9244
ISSN-L: 1584-9244

The Science Behind “Man Flu”


The aim of this study was to reveal the differences in male versus female response to viral respiratory illnesses, such as influenza. Estradiol may offer an immuno-protective effect while testosterone may lead to immunosuppression, explaining the higher morbidity and mortality rate of viral upper respiratory infections in men compared with women. The immune system is essential, not only in infectious diseases, but also in understanding autoimmune diseases, HIV infection, and oncology.



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