Although biliary tract malignancies are very rare tumors, they are associated with very high rates of mortality due to the fact that they remain clinically asymptomatic for a long period of time.
In order to improve the outcomes of these patients’, serum tumor markers measurements were proposed as part of the diagnostic and follow up protocol of these cases. This is a literature review regarding the role of tumor markers determination (CEA, CA 125, CA 19-9 and AFP) in cases with biliary tract cancer.
Tumor markers in biliary malignancies
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