Introduction. Lipid metabolism disorder is recognized as one of the risk factors for vitamin D deficiency, and the amount of adipose tissue is crucial in its metabolism and biological role. Childhood obesity is an important public health problem in Ukraine, especially among adolescents.
The objective of the study was to determine peculiarities of the prevalence and risk factors for vitamin D deficiency in overweight and obese adolescents in Ukraine.
Material and methods. 146 children, aged 12 to 17 years, with excessive weight and obesity, and 63 healthy children with normal body weight were examined. The vitamin D status was determined by the level of 25(OH) D in blood serum. The multiple logistic regression analysis was used to determine the risk factor affecting the development of vitamin D deficiency.
Results. The study has established that the average level of 25(OH) D in adolescents with normal body weight was 19.76±4.28 ng/mL, in adolescents with excess body weight 15.24±3.47 ng/mL, and in obese children 13.87±2.71 ng/mL. The prevalence of vitamin D deficiency in overweight adolescents was 70.62%, and in adolescents with obesity 77.19%.
Conclusions. The study has established the main risk factors and prevalence features for vitamin D deficiency in overweight and obese adolescents.
Keywords: vitamin D, children, calcidiol, prevalence, obesity.
Abbreviations: 25(OH)D – 25-hydroxycholecalciferol, calcidiol; С.I. – Confidence interval (95%); OR – Odds ratio; B – Beta, regression coefficient; S.E. – Standard error.
Address for correspondence:
Department of Pediatrics №2, State Institution of Higher Education “I. Horbachevsky Ternopil State Medical University of the Ministry of Health of Ukraine”, Ternopil, Ukraine
Address: 46001 Ternopil, Maydan Voli, 1, Ukraine
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